- The duration of crying is evaluated. The longer the crying, the higher the score.

- At least > 3 days / week for 1 week or more, assessed by the parents, without any other obvious cause.

- Crying relates to colic. Colic is defined as > 3 hours crying / day for at least 3 days during 1 week and since at least 1 week.

- Up to 3 hours of crying / day accounts for a score of 3.


Age: > 2 weeks, < 4 months


* Should only be considered if the child was crying for 1 week or more, assessed by the parents and without any other obvious cause.

- Using the score for grading the regurgitation.¹

- Rates the regurgitated volume and severity of the regurgitation.


Age: > 2 weeks, < 6 months


1- Vandenplas Y, Hachimi-Idrissi S, Casteels A, Mahler T, Loeb H. A clinical trial with an “anti-regurgitation” formula. Eur J Pediatr. 1994;153:419-23.

Using the well established Bristol stool scale to evaluate the consistency of the stools.¹



For at least one week

1- Lewis SJ, Heaton KW. Stool form scale as a useful guide to intestinal transit time. Scand. J. Gastroenterol.1997; 32: 920–4.

An easy way to apply score based on an estimation of the surface covered by the dermatitis, using the surface estimation drawings from burns.

Estimated surface
0 = 0
< 1/3rd = 1
1/3-2/3rd = 2
> 2/3rd = 3

Respiratory symptoms are considered in the CoMiSS^® although they have been given less importance (lower weighting) because most of the time chronic cough, runny nose and even wheezing are caused by viral infections.

However, respiratory symptoms can be caused by cow’s milk:

- Chronic cough
- Runny nose
- Wheezing